Platelet functionality in cold‐stored whole blood
نویسندگان
چکیده
منابع مشابه
Platelet-leukocyte cross talk in whole blood.
Thrombosis and inflammation involve complex platelet-leukocyte interaction, the details of which are not fully elucidated. Therefore, we investigated cross talk between platelets and leukocytes in whole blood, under the following physiological conditions: at 37 degrees C, with normal calcium concentrations, and with shear force. Platelet P-selectin and leukocyte CD11b expression were used to mo...
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A quantitative high yield method utilizing isosmotic arabino-galactan (Stractan) solutions and isopycnic centrifugation was developed to isolate and to fractionate total human platelet populations into density-dependent subpopulations. Isolated platelets were free of factor VIll/von Willebrand factor and other plasma proteins. They responded to ADP, epinephrine, and collagen with a sensitivity ...
متن کاملHeterogeneity of Human Whole Blood Platelet
A quantitative high yield method utilizing isosmotic arabino-galactan (Stractan) solutions and isopycnic centrifugation was developed to isolate and to fractionate total human platelet populations into density-dependent subpopulations. Isolated platelets were free of factor VIll/von Willebrand factor and other plasma proteins. They responded to ADP, epinephrine, and collagen with a sensitivity ...
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To help clarify the mechanism of propofol-induced vasodilation, we investigated whether propofol, at concentrations ranging from 10(-6) to 10(-3) M, inhibited platelet aggregation in human whole blood. Propofol inhibited platelet aggregation induced by adenosine diphosphate, collagen, or arachidonic acid in a concentration-dependent manner, with a 50% inhibited concentration (micromol/L) of 136...
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We examined platelet aggregation in platelet-rich plasma (PRP) and in whole blood from two patients with Glanzmann's thrombasthenia. In PRP, aggregation was measured by monitoring the changes in light absorbance that occurred in response to aggregating agents; to measure platelet aggregation in whole blood, we used a platelet counting technique. In PRP, the patients' platelets showed defective ...
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ژورنال
عنوان ژورنال: ISBT Science Series
سال: 2019
ISSN: 1751-2816,1751-2824
DOI: 10.1111/voxs.12501